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Intuitive Surgical vs Merck (ISRG vs MRK)

Intuitive Surgical (ISRG) vs Merck (MRK) in plain English: P/E, growth, margins, debt and dividend side by side, key differences and which fits each investor profile.

Intuitive Surgical (ISRG) and Merck (MRK) compete in healthcare and pharma. Here are Intuitive Surgical and Merck side by side with their real figures as of November 4, 2026: what sets them apart, which fits each kind of investor and the most common questions, without telling you whether to buy Intuitive Surgical or Merck.

Intuitive Surgical vs Merck: the figures

FigureIntuitive SurgicalMerck
Share price$482.10 (November 4, 2026)$150.36 (November 4, 2026)
Market cap$170.3 billion$371.0 billion
P/E (TTM)58.3x151.9x
Forward P/E38.7x16.7x
Revenue growth (quarter)+21.7%+4.7%
Net margin (TTM)25.5%3.6%
Net debt / EBITDANet cash2.9x
Dividend yield0.00%2.35%
Beta1.440.12

Intuitive Surgical and Merck figures from Yahoo Finance, the same source the Fintols analysis uses, retrieved on November 4, 2026; N/A means that Intuitive Surgical or Merck figure is not available, and we never estimate it.

3 key differences between Intuitive Surgical and Merck

  1. Valuation: Merck trades at 151.9x its annual earnings and Intuitive Surgical at 58.3x; the market pays more for each dollar of Merck profit, usually because it expects more growth.
  2. Profitability: for every 100 of sales, Intuitive Surgical keeps 25.5 as net profit and Merck keeps 3.6.
  3. Volatility: Intuitive Surgical stock moves more (beta 1.44) than Merck (beta 0.12); the higher the beta, the more it amplifies market swings.

Intuitive Surgical or Merck: which fits your profile

Neither Intuitive Surgical nor Merck wins on everything, and owning both is also an option: spreading money across several companies or an index fund reduces what rides on each one.

How Intuitive Surgical and Merck make money

Intuitive Surgical (ISRG)

Intuitive Surgical sells the da Vinci surgical robot and the Ion lung biopsy system to hospitals. Its biggest revenue source is instruments and accessories used up in each procedure, followed by system sales and leases and service contracts. The United States is its main market, with growing international sales. Full Intuitive Surgical analysis.

Merck (MRK)

Merck & Co. reports two segments. Pharmaceutical, by far the larger, sells Keytruda, its top cancer immunotherapy, the HPV vaccine Gardasil, Winrevair, Bridion and diabetes drugs like Januvia. Animal Health sells medicines and vaccines for pets and livestock, including the Bravecto flea and tick treatment. Full Merck analysis.

Frequently asked questions: Intuitive Surgical vs Merck

Is Intuitive Surgical or Merck the better stock?

Choosing between Intuitive Surgical and Merck depends on what you are looking for. Intuitive Surgical is growing faster right now, and Intuitive Surgical trades on the lower P/E. Fintols does not tell you whether to buy Intuitive Surgical or Merck: it shows you the differences so you can decide.

Which pays a higher dividend, Intuitive Surgical or Merck?

As of November 4, 2026, Merck yields 2.35% and Intuitive Surgical pays none. Also check how much of their profit Intuitive Surgical and Merck pay out: if it is more than they earn, it cannot last.

Which is more expensive, Intuitive Surgical or Merck?

On P/E, Merck (151.9x) is more expensive than Intuitive Surgical (58.3x) as of November 4, 2026. A higher P/E can be justified if earnings grow faster, so compare it with each company's growth in the table.

Can I own both Intuitive Surgical and Merck?

Yes. Many people spread their money across several companies, such as Intuitive Surgical and Merck, or use index funds so they do not depend on just one. If you are starting out, decide how much you want to invest and for how long before buying Intuitive Surgical or Merck.

More comparisons with Intuitive Surgical or Merck

More companies like Intuitive Surgical and Merck: healthcare and pharma stocks. Educational content about Intuitive Surgical and Merck, not investment advice.